The assortment has pharmacological agents in the form of:
- intramuscular injections;
- injections into the joint itself;
- creams, ointments.
In severe forms of joint diseases and a deterioration in the patient’s well-being, the doctor usually prescribes stronger drugs. They help fast. It’s about injections in the joint. Such drugs do not spoil the gastrointestinal tract. In milder forms of the disease, the specialist prescribes the administration of tablets, intramuscular injections. The use of creams and ointments is always recommended, as an addition to the complex of basic therapy.
Shishkevich Vladimir, orthopedic and traumatologist, project editor-in-chief ExpertNews.
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- Joint ointments
- New generation anti-inflammatory non-steroid drugs
- Contraindications and side effects
- Anti-inflammatory drugs for joints
- Prescribing medications in the treatment of articular pathologies
- The mechanism of action on the body
- List of anti-inflammatory drugs for joints
- Nonstero >
- Non-selective NSAIDs
- Hormonal drugs
- Brief conclusions
- List of joint pills: for pain and inflammation
- Mechanism of action
- Groups of drugs and adverse reactions
- Disease-modifying antirheumatic drugs
- Glucocorticostero >
- Joint and cartilage preparations
- How to choose the right drug
- Anti-inflammatory drugs for joints
- Joint steroid anti-inflammatory drugs
- Joint non-steroidal anti-inflammatory drugs
- Topical non-steroidal anti-inflammatory and pain medications for joints
- Nonsteroidal anti-inflammatory drugs (NSAIDs) for the treatment of joints
- Characteristics and classification of NSAIDs
- Indications for use of NSAIDs
- Treatment Scheme
- NSAIDs for oral administration:
- NSAIDs for topical use
- Solutions for injection
- Side effects and overdose of NSAIDs
- Joint anti-inflammatory pills
- How do anti-inflammatory drugs work?
- Causes of joint inflammation
- Classification of drugs
- Ointments and plasters
There are such effective NSAIDs (funds):
- “Indomethacin” (another name is “Metindol”). Tablets for joint pain relieve inflammation, have an antipyretic effect. The drug is drunk twice or thrice a day, 0,25-0,5 g.
- Etodolac (Etol Fort). Available in capsules. It quickly anesthetizes. It acts on the focus of inflammation. It should be drunk one tablet 1-3 times after a meal.
- “Aceclofenac” (“Aertal”, “Diclotol”, “Zerodol”). Diclofenac analog. The drug is taken on a tablet twice a day. The medicine often causes s >
- With ibuprofen (Dolgit, Nurofen). Anti-inflammatory and analgesic ointment for joints with such a main component will help those with arthritis and trauma. Acts very fast.
- With diclofenac (Voltaren, Diklak, Diklofenak, Diklovit). Such medicinal ointments warm up, relieve pain and block inflammatory processes. Quickly help those who are difficult to move.
- With ketoprofen (Ketonal, Fastum, Ketoprofen Vramed). Prevent blood clots. If the ointments are used for too long, a rash may appear on the body.
- With indomethacin (Indomethacin Sofarma, Indovazin). They act similarly to ketoprofen-based drugs, but less intensively. They warm well, help with rheumato >
Allocate such NSAIDs for injection:
- Diclofenac. Relieves inflammation, pain, is prescribed for severe diseases. Intramuscularly administered 0,75 g of the drug once or twice a day.
- Tenoxicam (Texamen L). Soluble powder for injection. 2 ml per day is prescribed for mild pain syndrome. The dose is doubled and a five-day course is prescribed for gouty arthritis.
- “Lornoxicam” (“Larfix”, “Lorakam”). 8 mg of the drug is injected into the muscle or vein once or twice a day.
New generation anti-inflammatory non-steroid drugs
More modern, and therefore more effective means:
- Movalis (Mirlox, Arthrosan). A very effective drug, manufactured in tablets, solution for injections, candles. Virtually no side effects. For injections use 1-2 ml of solution per day. Tablets are taken at 7,5 mg once or twice a day.
- “Celecoxib.” It has no fatal effect on the stomach. Take one or two tablets per day, but not more than 0,4 g of the drug per day.
- Arcoxia. The drug is in tablets. Dosage is prescribed depending on the severity of the disease.
- “Nimesulide.” Available in tablets, dilution bags, in gel form. The dose is determined by the doctor, as are the rules for admission.
Contraindications and side effects
The use of a group of non-steroidal anti-inflammatory drugs for the treatment of joints is prohibited with:
- component intolerance;
- an ulcer;
- diseases of the liver, kidneys;
- pregnancy and lactation;
- anemia, high blood pressure;
- heart disease
When taking medication, the following side effects may occur:
- digestive system disorders;
- pressure increase;
- impaired blood clotting;
- bleeding from the nose;
- impaired kidney function;
Anti-inflammatory drugs for joints
In the treatment of articular pathologies, the main problem is the fight against the inflammatory process. Non-steroidal anti-inflammatory drugs for the treatment of joints are the main means in solving this problem, at the same time giving a good result and not causing such harm as steroid drugs. However, NSAIDs also have their drawbacks both among contraindications and side effects.
Prescribing medications in the treatment of articular pathologies
Anti-inflammatory drugs are involved at every stage of the entire course of treatment. NSAIDs are the main medications used against inflammation in pain in the joints of the arms and legs. Steroidal anti-inflammatory drugs for the treatment of joints are used for severe forms of diseases, during periods of exacerbations, when non-steroidal drugs are powerless.
The mechanism of action on the body
NSAIDs act on COX receptors. 1st generation medications indiscriminately inhibit COX-1 and COX-2, which affects the damage to the mucosa of the gastrointestinal tract. The second generation of drugs acts exclusively on COX-2, causing significantly less damage to the digestive tract. However, the active substances of these drugs negatively affect the heart and can lead to complications, in addition, they should be used together with anticoagulants. Glucocorticosteroids artificially introduce anti-inflammatory hormones produced by the adrenal glands into the body. A very powerful effect is accompanied by the rapid development of side effects, in particular, cartilage fiber is destroyed.
List of anti-inflammatory drugs for joints
NSAIDs are effective both for relieving inflammation and for pain relief. They are divided into two groups: COX inhibitors and selective new-generation anti-inflammatory drugs. They have approximately the same effect in strength, but have various contraindications and side effects. Painkillers of the first group have a strong destructive effect on the digestive tract, it is recommended to use after meals, drinking plenty of water. Painkillers are available in the form of tablets, injections, like suppositories, ointments or creams.
List of drugs of the 1st group:
Ibuprofen is a derivative of phenylpropionic ac >
For joint pain, drugs such as selective inhibition of COX-2 are used:
- “Meloxicam” medication based on Movalis. It has a prolonged action – 1 tablet per day and good tolerance – can be taken for years.
- “Celecoxib” belongs to the coxib group. Effective analgesic and anti-inflammatory for arthritis and arthrosis, good tolerance for the digestive tract.
- “Nimesulide” is an effective remedy for inflammation and pain, and also has an antioxidant effect, which inhibits the destruction of cartilage tissue.
Contraindications to taking NSAIDs:
- pregnancy and breastfeeding,
- pathological diseases of the gastrointestinal tract.
It is not recommended to take NSAIDs tablets for joint inflammation for more than a week due to the negative effect on the gastrointestinal tract. Effectively replaced by joint injections and anti-inflammatory ointments with the same active component of NSAIDs.
Medications that relieve almost any joint inflammation. In severe arthritis, they are interchangeable only with expensive biological products. They can be used as enhanced pulse therapy – in overdoses in extreme conditions. Used for short periods, have strong side effects, in particular, the destruction of cartilage and ligaments. Steroid ointments and gels, creams, as well as injections for joints of the knee, shoulder, lower back, pelvis, and, if necessary, in the form of tablets are mainly used. The names of some drugs in this group:
Side effects of corticosteroids:
- violation of the metabolism of sodium and water, as a result of swelling,
- the growth of blood sugar, it is possible the acquisition of steroid diabetes,
- hypocalcemia and osteoporosis,
- deterioration of tissue regeneration,
- depression of immunity
- decreased blood coagulation.
The use of NSAIDs and glucocorticosteroids in the treatment of arthrosis and arthritis should be carried out taking into account their specific effects on the body, both positive and negative. Treatment with such drugs without monitoring and manipulation by the doctor can lead to serious health consequences in general and worsening of the disease in particular.
List of joint pills: for pain and inflammation
Mechanism of action
All tablets used for joint inflammation are divided into several groups:
- Analgesics. The action of non-narcotic analgesics is also aimed at blocking the COX-2 enzyme and the production of prostaglandins, which disrupts the transmission of pain impulses. The effects of their use are the same as those of NSAIDs. Narcotic analgesics have an analgesic effect due to the effect on the opiate receptors in the central nervous system to block pain.
- NSAIDs. They have anti-inflammatory, analgesic and antipyretic effects. They are realized by blocking the enzyme type 2 cyclooxygenase. This leads to a decrease in the production of prostaglandins, which are responsible for inflammation, pain, redness, local temperature increase and impaired limb function.
- Chondroprotectors. Another pill for pain in the joints of the legs. Thanks to glucosamine and chondroitin, they also have an anti-inflammatory effect by reducing the release of interleukins and prostaglandins. In addition, drugs of this group slow down the destruction of cartilage tissue and, over time, restore it. This slows down the course of the pathological process. Chondroprotective tolerance is significantly better than NSAIDs.
- Disease-modifying antirheumatic drugs (BMARP). They are also used to treat joint inflammation. Each specific drug from this group is aimed at a specific link in the pathological process. But the result from their use is the same – the course of the disease slows down.
- Glucocorticosteroids. Such anti-inflammatory joint tablets have their effect due to the blocking of the enzymes nuclease, phospholipase A2, protease. They destroy tissue, contribute to the development of inflammation. Corticosteroids reduce the permeability of the vessel wall, reducing swelling.
- Preparations for ligaments, cartilage and joints.
Groups of drugs and adverse reactions
Let us consider in more detail the representatives of each of the groups of drugs for the treatment of joints, their effect and adverse reactions.
Analgesics are included in the list of essential drugs for the treatment of inflamed joints. They can be divided into the following groups:
- Non-narcotic analgesics containing acetaminophen (Tylenol).
- Narcotic anesthetics. Relate to strong painkillers for joint pain. They are prescribed only by the attending physician; they are not released without a prescription.
- Combined painkillers for joint pain. They are also strong painkillers. Consist of opioid and non-narcotic substance acetaminophen. Recommended for very severe pain.
The following medicines are referred to combined painkillers for pain in the joints of the legs and hands:
Taking medications from this group may be accompanied by undesirable reactions such as:
- impaired hepatic and renal function;
- psychomotor agitation;
- pain in epigastrium;
- decrease in blood sugar concentration;
- anemia, a decrease in the number of platelets, white blood cells;
- oppression of the respiratory, thermoregulatory, cough, vasomotor centers, dependence (when taking narcotic analgesics).
NSAIDs are the most common painkillers for joint pain. The following representatives belong to this group:
The best tablets for pain in joints and muscles from the NSAID group are Ketorolac, Indomethacin, Diclofenac, Ketorol. Ibuprofen and aspirin are inferior to them in analgesic effect.
Undesirable effects of NSAIDs:
- with prolonged use, which is necessary, for example, with pain in the joints of the knees, ulcers and erosion of the gastrointestinal tract are formed;
- heart attacks;
- arterial hypertension;
- impaired renal function;
- aspirin bronchial asthma.
Disease-modifying antirheumatic drugs
These drugs are used in case of arthrosis of the knee and other joints. In addition, BMARP help to cope with arthritis of various origins (rheumatoid, psoriatic, idiopathic). Preparations of this group are used only at the risk of destruction of the joint cavity. They can be taken in courses without any consequences. However, the duration of treatment is a minus – a noticeable effect will appear after a few weeks, sometimes months.
The following drugs are included in the list of tablets from joints from the BMARP group:
Side effects include increased sensitivity to sunlight, increased hair growth, sore throat, diarrhea, a decrease in the number of blood cells.
Chondroprotectors are joint repair pills. Chondroitin and glucosamine, which restore cartilage, over time help to get rid of pain in the joints of the legs. The active substances can be contained in the preparations either in isolation or in combination.
Joint and cartilage repair pills containing glucosamine:
Joint treatment tablets containing chondroitin:
The disadvantage of this group of drugs is the cost and need for long-term use.
Side effects of chondroprotectors include:
- nausea, vomiting, abdominal pain;
- allergic reactions.
Glucritocosteroids are used for severe joint pain. These pills for joint inflammation are prescribed when another therapy is ineffective. Corticosteroids can be injected directly into the joint cavity.
Often use the following pills for pain in the legs and joints of a hormonal nature:
For intraarticular injections apply:
“Liquid prostheses” replace joint fluid, improve metabolism in the cartilage. The downside is the high cost.
Prolonged use of glucocorticoids or abrupt withdrawal threatens with the following undesirable effects:
- peptic ulcer;
- Cushing’s syndrome;
- bone necrosis;
- violation of growth and development.
Self-administration of corticosteroids is prohibited! This can have dire consequences.
Joint and cartilage preparations
With the occurrence of articular pathology along the way, not only cartilage is affected, but also ligaments and muscles. Therefore, the ligamentous, muscular apparatus and cartilage need support.
To restore and strengthen cartilage and joint will help:
- Glucosamine – tablets necessary for cartilage and joints. This is the precursor of glycocsaminoglycan, from which cartilage tissue is built. Glucosamine helps relieve joint pain when moving, especially when treating a knee joint.
- Chondroitin sulfate – used as tablets for bones and joints, contributing to the deposition of calcium in bone tissue. It is also one of the main components of cartilage. Increasing collagen synthesis strengthens ligaments. Enhances the production of intraarticular flu >
With joint damage, it is necessary to maintain a ligamentous apparatus. For ligaments and joints apply:
- omega-3 fatty acids;
- hyaluronic acid – is part of the ligaments in the form of glycosaminoglycan;
- Bromelian – proteolytic enzymes used as painkillers for joint pain;
- vitamins B6, C, E;
- minerals – magnesium, niacin, selenium, zinc.
How to choose the right drug
When choosing pills for joint treatment, you can not rely solely on reviews and advertising. Not everyone approaches this or that remedy. Therefore, it is imperative to be examined, to take an x-ray of the articular region.
Only on the basis of this study, the doctor will be able to put the stage of the disease and prescribe the necessary treatment.
The choice of drug depends not only on the stage of the disease, but also on age, the type of pathology, the necessary active substance and general health.
The first should be prescribed drugs that stop the pain syndrome. Next, drugs that eliminate the inflammatory process are used. Then – medications to restore cartilage, muscle and ligaments.
At the first stage of the process, tablets are used in tablet form. Damaged cartilage requires injection.
An important criterion for choosing a drug is price. The cost of Russian funds is much lower, but the effect of their use is noticeable only at the first stages of the pathology.
Currently, the pharmaceutical market provides many pills for the treatment of joints. Although many drugs are dispensed without prescription, indications for prescribing the drug should be determined by the doctor after the examination.
This is necessary, since each group of drugs has its own side effects and acts on one or another link in the pathological process. Self-treatment can lead at best to loss of funds, at worst – to serious consequences.
Anti-inflammatory drugs for joints
All pathologies of the musculoskeletal system are accompanied by pain and inflammation. In the early stages of the development of diseases, these signs are poorly expressed, and physiotherapy, gymnastics and local influences are enough to eliminate them. With the progression of diseases, it is necessary to use anti-inflammatory drugs for the joints. Depending on the origin of the active ingredients, they are classified into 2 large groups – steroidal and non-steroidal agents. Each type has a number of features, advantages and disadvantages.
Joint steroid anti-inflammatory drugs
The described type of medication is the most effective and fastest. Such drugs are based on chemical compounds that are similar in molecular structure to cortisone secreted by the human body.
Usually, steroidal anti-inflammatory drugs for joints are used in the form of injections. With the help of injections, the maximum therapeutic effect is achieved, especially if they are performed directly into the affected area, intraarticular space.
It is worth noting that in severe cases of joint diseases, blockades alone are not always enough. Therefore, glucocorticosteroids can be recommended for systemic use.
Joint non-steroidal anti-inflammatory drugs
This group of drugs has a less pronounced effect, but it is quite enough to stop the moderate, moderate and moderate stages of pathologies of the musculoskeletal system. Moreover, such medications cause much less negative side effects and consequences than steroids do not provoke addiction.
Most often, anti-inflammatory drugs for the joints are used in the form of tablets:
- Rapten Rap />
- Metindole Retard;
Most of these medicines are sold in other dosage forms, including injectable solutions.
Topical non-steroidal anti-inflammatory and pain medications for joints
Mild forms of articular pathologies do not always involve the introduction or internal administration of NSAIDs. You can stop the pain and reduce the severity of inflammation by applying local medicines:
- Ortofen ointment;
- Voltaren emulsifier;
- Nurofen Gel;
- Diclonate P;
- Final gel;
Nonsteroidal anti-inflammatory drugs (NSAIDs) for the treatment of joints
Inflammation of the joints and surrounding soft tissues is a frequent companion of disorders of the musculoskeletal system. Conservative drug treatment of pathologies is aimed at relieving pain, restoring cartilage functions and preventing its further destruction. Doctors prescribe non-steroidal anti-inflammatory drugs for the treatment of joints at all stages of the disease.
Characteristics and classification of NSAIDs
Nonsteroidal anti-inflammatory drugs (NSAIDs) are cyclooxygenase blockers, a group of enzymes responsible for the development of symptoms of pain and inflammation. Medicines have a pronounced analgesic and anti-inflammatory effect, but, unlike glucocorticoids, have fewer side effects.
The following groups of NSAIDs are distinguished. By chemical composition:
- Acidic – the main active ingredient are derivatives of organic acids (salicylic, indoleacetic, pheniacetic, propionic);
- Non-acidic – alkanones or sulfonamides are used as the active component.
According to the mechanism of action:
- Non-selective – inhibit all types of cyclooxygenase;
- Selective – selectively inhibit only cyclooxygenase-2, thereby reducing the likelihood of development of pathologies from the digestive system.
By release form:
- Drugs for oral administration (tablets, granules, capsules);
- Solutions for intramuscular injection;
- Medicines for external use.
The following is a list of the main non-steroid medications for the treatment of joints located by the strength of anti-inflammatory action:
- Indomethacin (Metindol, Indocollyr);
- Diclofenac (Diclovit, Ortofen);
- Piroxicam (Final Gel);
- Ketoprofen (Flamax, Flexen);
- Naproxen (Apranax, Sanaprox);
- Ibuprofen (Dolgit, Faspik, Nurofen);
- Aspirin and its derivatives.
Nonsteroidal anti-inflammatory drugs are most effective for mild to moderate joint damage. In case of persistent pain, glucocorticoids are injected into the synovial cavity. In case of serious irreversible damage to the joint, surgical intervention is indicated.
Indications for use of NSAIDs
In orthopedic practice, the main indications for taking NSAIDs are:
Rheumatic pathologies (rheumato >
All anti-inflammatory and analgesic preparations for the joints must be used strictly as prescribed by the orthopedist or rheumatologist. The duration and treatment regimen are developed individually, taking into account the age of the patient, the clinical picture, the presence of concomitant diseases.
NSAIDs for oral administration:
- Indomethacin. One tablet contains 25 mg of the active substance. Use one unit of the drug up to three times a day for 5-10 days. With insufficient effectiveness of anti-inflammatory therapy, an increase in the daily dose to 75-100 mg as prescribed by a specialist is allowed. The cost of one package is 60-250 rubles, depending on the dosage and number of tablets;
- Diclofenac. Each tablet contains 50 or 100 mg of diclofenac sodium. Use 50 mg of the drug three times a day. The average price is 15-50 rubles, depending on the dosage;
- Piroxicam. The drug is available in the form of capsules and tablets containing 10 or 20 mg of the active substance. With arthrosis and rheumatoid arthritis, you need to drink 10-30 mg of analgesic for a long time. In an acute gouty attack, 40 mg of the drug is prescribed once in the first 2 days, then for 4-6 days – 20 mg twice a day. The cost of packaging the drug in capsules is 50-60 rubles, in tablet form – 85-100 rubles;
- Ketoprofen. One tablet contains 100 mg of active ingredient. Drink one unit of the drug twice a day. The average price for a package is 130-160 rubles;
- Nimesulide. Each tablet contains 100 mg of active ingredient. For diseases of the musculoskeletal system, it is necessary to drink up to 200 mg of the drug per day. The cost of one package is 65-80 rubles;
- Ibuprofen. An anti-inflammatory drug is available in tablets containing 0,2 g of active ingredient. Adult patients are prescribed up to 0,6 g of medication three times a day. The price is 25-95 rubles, depending on the volume of packaging;
- Arcoxia. The drug of the latest generation is available in tablets of 60, 90 and 120 mg. Dosage is set individually. When using a product containing 120 mg of the active component, the duration of treatment should not exceed 8 days. The average cost is 300-600 rubles, depending on the dosage and packaging volume.
In order to reduce the risk of complications from the gastrointestinal tract, one should drink preparations with a large amount of still water or milk and at the same time take antacids.
For joint diseases, NSAIDs are prescribed as short a course as possible. If 5-7 days after the start of treatment with non-steroidal anti-inflammatory drugs there is no marked improvement, a change in the treatment regimen or the appointment of another group of medications is required.
For relapses of arthritis, I use Diclofenac in tablet form as the main drug. The drug quickly anesthetizes, relieves the symptoms of joint inflammation and improves the general condition.
Maria, 47 years old, St. Petersburg.
NSAIDs for topical use
Most often, local non-steroidal anti-inflammatory drugs are used to treat joints of the legs and other large joints. Ointments, gels and creams are effective for diseases and injuries of joints with mild symptoms, as well as in the postoperative period. The average price is 150-400 rubles, depending on the active substance and the amount of packaging. The most popular products for external use are:
- Nurofen, Dolgit – based on ibuprofen;
- Diclovit, Voltaren, – with diclofenac;
- Fastum, Ketonal – with ketoprofen;
- Final gel – based on piroxicam;
- Indovazinum – with indomethacin.
All non-steroidal ointments for the treatment of joints are evenly distributed with a thin layer over the affected areas of the body and rubbed lightly. A single dosage is 2-5 g, the frequency of use is up to 4 times a day. The duration of treatment should not exceed 2 weeks.
To eliminate moderate pain with knee arthrosis, I use local anti-inflammatory drugs Voltaren and Finalgel. Both drugs effectively relieve swelling and discomfort in the joint, are well absorbed and do not cause peeling of the skin.
Evgeny Mikhailovich, 65 years old, Samara.
Solutions for injection
NSAIDs are usually prescribed for severe pain, when funds for oral administration or local use are not effective enough. Most often used Diclofenac, Ibuprofen or their analogues. Injections of a non-steroidal anti-inflammatory drug for joint pain are administered intramuscularly, the standard course of treatment is 8 days.
The following contraindications to joint therapy with non-steroidal anti-inflammatory drugs are distinguished:
- Excessive sensitivity to the drug;
- Diseases of the digestive tract (especially when using NSAIDs inside);
- Hematopoiesis, bleeding tendency;
- Severe pathologies of internal organs, heart, blood vessels;
- Pregnancy and natural feeding.
Any anti-inflammatory drug prescribed by your doctor should be used with caution in case of asthma, diseases of the genitourinary system, in old age and after surgery.
Side effects and overdose of NSAIDs
The following side effects are noted during treatment of NSAID joints:
- Discomfort and pain in the abdomen, nausea;
- Stool disorder (constipation, diarrhea), increased gas formation;
- Allergic reactions of a different nature;
- Headache, anxiety, nervousness, sleep disturbances;
- Tachycardia, jumps in blood pressure;
- Rapid urination;
- Increased sweating, thirst, chills.
When using local NSAIDs, rashes, dryness and peeling of the skin in the area of contact with the drug are often diagnosed. Exceeding the therapeutic dose increases the risk of occurrence and the intensity of side effects. Treatment for an overdose is symptomatic.
Non-steroidal anti-inflammatory drugs are the first choice for joint diseases accompanied by pain and swelling. Medicines are most effective in the early stages of pathology.
Joint anti-inflammatory pills
The article describes the types of drugs for the treatment of joint inflammation. The therapeutic effects are indicated, various dosage forms are described, instructions for use are given.
Anti-inflammatory drugs for the joints are one of the most important in the treatment of arthritis, arthrosis and other joint pathology. The modern pharmaceutical market offers a huge number of names and dosage forms. Are joint preparations for inflammation really so diverse?
Pain is a harbinger of terrible pathologies that in a year or two can put in a stroller and make you disabled. Head doctor Goltsman: to completely restore the JOINTS and the BACK is simple, the most important thing.
How do anti-inflammatory drugs work?
The inflammatory process is a change in the structure of an organ, accompanied by a violation of its function. Anti-inflammatory drugs for joints block this process, contributing to the restoration of organ function.
The mechanism of their action is based on the blocking of inflammatory mediators – biologically active substances that stimulate the body’s defensive reaction in response to any pathology. As a result, tissue swelling decreases, microcirculation normalizes, and fever ceases.
Causes of joint inflammation
Why are joints inflamed?
The development of this pathological process can occur for various reasons:
- most often it is an injury to the joint with a violation of the integrity of its structures;
- reactive arthritis with infectious inflammation is not uncommon;
- Autoimmune inflammation or a complication of systemic diseases is much less common.
The inflammatory process in all cases develops according to general laws.
It will be most pronounced in arthritis – the causes of joint inflammation in this case will be either infectious or traumatic. The pathology is accompanied by severe pains, for many, not only the local, but also the general temperature rises with inflammation of the joints.
There is another type of arthritis – rheumatoid. In this case, the process is autoimmune in nature and there will be no severe intoxication.
Degenerative inflammatory diseases of the spine and joints are arthrosis with the addition of synovitis. Inflammation in this case is less intense.
Classification of drugs
All drugs with the indicated action can be divided into two main groups:
- Nonsteroidal anti-inflammatory. This includes drugs of selective (Movalis, Celebrex) and indiscriminate (Diclofenac, Ibuprofen) actions.
- Corticosteroids. These are hormonal drugs, one of the main effects of which is to reduce the inflammatory process. These include Metipred, Hydrocortisone.
Groups of drugs are also distinguished that do not have a pronounced anti-inflammatory effect and reduce inflammation only indirectly. So antibiotics are used for inflammation of the joints. By suppressing the microbial flora, they contribute to the disappearance of signs of inflammation.
In addition, anti-inflammatory drugs for joints can be classified depending on the dosage form:
- for external use – ointments, gels, creams, plasters;
- for internal use – tablets, capsules;
- means for introducing into the joint cavity.
Depending on how pronounced inflammatory diseases of the joints, different types of drugs are used.
Tablets for inflammation of the joints are used in almost all diseases. For some, they form the basis of therapy, for others they are used as symptomatic treatment. This will depend on what the joints become inflamed with.
Table 1. Tablets in the treatment of articular pathology:
|Preparation||Therapeutic effect||Показания||Contraindications||Side effects||Instructions for use|
|Ibuprofen||Included in the NSAID group, is a non-selective drug. Provides anti-inflammatory and analgesic effects.||They are used in the treatment of various inflammatory joint diseases – arthritis and arthrosis.||Individual intolerance, gastrointestinal tract pathology, impaired blood coagulation, pregnancy.||Nausea with vomiting, heartburn, upset stool. Less commonly, headache, palpitations.||If the joint is inflamed, the drug is taken 1 tablet 3 times a day.|
|Aertal||Included in the NSAID group, is a non-selective drug. Suppresses inflammation, reduces pain.||Used as a symptomatic treatment for inflammatory joint diseases.||Gastrointestinal pathology, severe liver and kidney diseases, pregnancy, childhood.||Disruption of the digestive tract, dizziness, an allergic reaction like hives.||Take one tablet twice a day with a sufficient amount of liquid.|
|Movalis||Tablets for inflammation of the joints from the NSAID group, which have a selective effect.||Indicated for the symptomatic treatment of inflammatory and degenerative joint diseases.||Bronchial asthma, stomach ulcer, severe pathology of the liver and kidneys.||Dizziness, bloating, increased bleeding.||Take 1-2 tablets per day.|
|Celebrex (photo)||A drug from the NSAID group with a pronounced selective effect.||Therapy of inflammatory and degenerative joint diseases.||Bronchial asthma, stomach ulcer, pregnancy.||Stool disorder, allergic reactions.||Take 1 tablet per day.|
|Metipred||Corticosteroid with a pronounced anti-inflammatory effect.||Used for severe forms of arthritis and arthrosis.||Individual intolerance.||Debut of diabetes, dyspeptic phenomena, arrhythmias.||The dosage is determined by the doctor individually.|
|Arava||Monoclonal antibodies – the drug has anti-inflammatory and immunosuppressive effects.||Indicated for the treatment of rheumatoid and psoriatic arthritis.||Individual intolerance, pregnancy, children’s age.||Dyspeptic symptoms, dizziness, allergic reactions.||Take 1 tablet per day.|
Only a doctor can prescribe such funds. To stop side effects, you may need to take additional drugs. For example, anti-inflammatory non-steroidal drugs for joints adversely affect the stomach, so they are taken simultaneously with omeprazole.
Ointments and plasters
Anti-inflammatory ointments for joints are widely used. External dosage forms can reduce local inflammatory phenomena, eliminate swelling and pain in the joints.
Table 2. Means for local treatment of joints:
|Name||Therapeutic effect||Показания||Contraindications||Side effect||Mode of application|
|Voltaren||The drug from the NSAID group has anti-inflammatory and decongestant action.||Symptomatic treatment of joint inflammation.||Pregnancy, childhood, wounds and abrasions at the site of application.||Redness and peeling of the skin.||Anti-inflammatory ointment for joints is used to apply to the skin with massage movements three times a day.|
|Dolobene||A drug with a combined composition – heparin, dimethyl sulfoxide, dexpanthenol.||Used to treat arthritis and joint injuries.||Severe liver and kidney disease, pregnancy, bronchial asthma.||Redness of the skin.||Apply to the skin with a thin layer twice a day.|
|Viprosal||Ointment for inflammation of joints with a combined composition – viper venom, salicylic acid, turpentine, camphor.||Used to treat arthrosis.||Skin diseases, fever, severe liver and kidney pathology, pregnancy.||Rarely – allergic reactions.||Apply to the skin once a day, rubbing lightly.|
|Ketonal patch||The drug from the NSAID group.||It is used to treat arthritis and arthrosis of various origins.||Wounds and abrasions on the skin, pustules, individual intolerance.||Allergic reactions.||The patch is applied to the affected joint for up to 12 hours.|
|Dolgit||The drug from the NSAID group.||Anti-inflammatory gel for joints is used for arthritis, arthrosis, and injuries.||Individual intolerance.||Redness of the skin.||Apply a thin layer to the skin twice a day.|
Ointments have fewer side effects, but it is better to consult a specialist before using them.