Injections Movalis instructions for use of the drug

Movalis is available in the form of an injection, which has anti-inflammatory, analgesic and antipyretic effects. The drug is used to reduce the severity of acute pain that occurs during relapses of pathologies of the musculoskeletal system. The use of injections of Movalis in the treatment of osteochondrosis of various localization, arthritis, arthrosis, intervertebral hernias is practiced.

The composition and release form of the drug

German, Spanish, Italian manufacturers produce an injection solution of Movalis in the packaging of 1,5 ml. It is a clear, yellowish liquid with a slight greenish tint without any specific odor. The solution is placed in colorless glass ampoules, which are 3 or 5 each in the contour cells of plastic blisters. Secondary packaging – a cardboard box with an annotation embedded inside. The active ingredient of the drug is meloxicam. The auxiliary composition is represented by the following components:

  • meglumine;
  • glycofurol;
  • poloxamer;
  • glycine;
  • sodium hydroxide;
  • sodium chloride;
  • water for injection.

Additional ingredients provide almost 100% bioavailability and maximum absorption of meloxicam in tissues damaged by pathology, as well as synovial fluid. In addition to the injection, the Movalis therapeutic line includes tablets, rectal suppositories, and suspension.

Operating principle

The therapeutic effect of Movalis is due to its active ingredient meloxicam, which is a non-steroidal anti-inflammatory drug (NSAID). It inhibits the enzyme cyclooxygenase, stimulating the biosynthesis of mediators of pain, inflammation, fever – prostaglandins.

Meloxicam refers to selective NSAIDs. It selectively blocks cyclooxygenase-2, prevents the production of prostaglandins directly in inflammatory foci, and not in the kidneys and gastrointestinal tract. Such selective action of Movalis explains a narrower list of its side effects compared to non-selective NSAIDs.

Meloxicam prevents the migration of leukocyte and macrophage tissues into damaged by the destructive or inflammatory process. This prevents the formation of edema, normalizes microcirculation, lymph and blood circulation. Parenteral administration of the solution allows you to quickly stop acute and chronic inflammatory processes in the joints, eliminate pain, reduce general and local body temperature.

In what cases is Movalis applied

Movalis injection solution is intended for symptomatic therapy of inflammatory and degenerative-dystrophic pathologies of the musculoskeletal system. It is prescribed to patients with relapses of cervical, thoracic, lumbosacral osteochondrosis, intervertebral hernias. The drug is used to relieve acute pain in arthritis – rheumatoid, gouty, psoriatic, reactive, infectious. Indications for the use of the drug are also such joint diseases:

Parenteral administration of Movalis can be prescribed to patients with rheumatism, radiculitis, muscle pain. It is used for injuries (fractures, dislocations, torn ligaments, tendons) to relieve acute, piercing pain.

Dosing and Administration

Movalis injection solution is intended for deep injection into the gluteus maximus muscle. Single doses of the drug are determined by the attending physician, taking into account the severity of symptoms, the type of pathology, and the general health of the patient. A single dose of 15 mg of Movalis is sufficient to eliminate acute pain. If necessary, reuse of the drug is allowed. Patients with severe liver and kidney pathologies predisposed to allergic reactions are prescribed a dose of 7,5 mg.

Shishkevich Vladimir, orthopedic and traumatologistShishkevich Vladimir, orthopedic and traumatologist, project editor-in-chief ExpertNews.

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For adults

Before the injection, the skin over the gluteus maximus muscle is treated with alcohol-containing antiseptic solutions. Before proceeding with the slow administration of the drug, make sure that the blood vessel was not injured with a needle. After removing it from the muscle, it is necessary to treat the skin with antiseptics again.

If a second injection is required, then it is carried out in another gluteal muscle. If severe pain appears during the procedure, stop the introduction of the solution. In patients with hip arthroplasty, an injection is made into the muscle of the opposite buttock.

For children

Movalis injection solution is not used in the treatment of children under 18 years of age. If treatment with meloxicam preparations is necessary, tablets of the same name or rectal suppositories in dosages calculated by the doctor can be used.

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For pregnant and lactation

Systemic agents that inhibit the production of prostaglandins from arachidonic acid, it is undesirable to use during the period of gestation and breastfeeding. When planning a pregnancy, doctors also recommend stopping the use of any dosage form of Movalis. Treatment with drugs with meloxicam increases the likelihood of miscarriage, congenital malformations.

In the initial stages of pregnancy, Movalis can be prescribed to a woman only in case of urgent need, when the use of safer drugs did not give the desired therapeutic result. An analgesic is used once in a minimum dose.

In the third trimester, Movalis therapy is not performed due to the high risk of bleeding, inhibition of uterine contractions, and violation of labor.

Meloxicam quickly passes into breast milk, therefore, when using it, lactation must be stopped for a while.

Contraindications and side effects

Movalis injections are not prescribed for patients who have hypersensitivity to its auxiliary ingredients and meloxicam. The drug is not used during relapses of erosive and ulcerative lesions of the stomach and duodenum, hyperacid or erosive gastritis. Contraindications to the use of Movalis are also active gastrointestinal bleeding, blood circulation and circulatory disorders.

The drug is not included in the therapeutic regimens of patients with severe renal, hepatic, heart failure, inflammatory intestinal pathologies, for example, Crohn’s disease or acute ulcerative colitis.

Vital system or organsPossible side effects of Movalis in the form of an injection solution
Lymphatic and circulatoryAnemia, leukopenia, thrombocytopenia, a change in the number of blood cells and the percentage of different types of white blood cells
ImmuneLocal and systemic allergic reactions that develop due to individual intolerance to the ingredients of the drug
nervousHeadaches, dizziness, impaired coordination of movements
sensesVertigo, conjunctivitis, visual disturbances, decreased visual acuity, tinnitus
CardiovascularIncreased blood pressure, sensation of a rush of blood to the face, increased heart rate
respiratoryBronchospasms in patients with hypersensitivity to HPV or acetylsalicylic acid
digestivePain in the abdomen and epigastric region, increased gas formation, constipation or diarrhea, bouts of nausea, vomiting, belching
Liver and biliary tractChanges in the functional parameters of the liver
Skin and deeper soft tissueAngioneurotic edema, itching, rashes, allergic reactions such as urticaria, erythema multiforme, photosensitivity
UrinaryUrination disorders, acute renal failure, changes in the functional parameters of the kidneys

Overdose

Excess single doses of Movalis are clinically manifested by drowsiness, fainting, nausea, vomiting, stomach pain, gastrointestinal bleeding, acute renal failure, arterial hyper- or hypotension, asystole, respiratory arrest. An antidote does not exist, but the use of colestyramine contributes to the faster elimination of meloxicam from the body.

special instructions

The use of a solution with meloxicam can cause a decrease in visual acuity, drowsiness, dizziness, and coordination disorder. This should be taken into account when performing work requiring increased concentration and attention. Doctors recommend abandoning driving during treatment with Movalis.

Drug Interactions

Using Movalis with other NSAIDs is not recommended due to a significant increase in the risk of ulceration of the gastric mucous membranes. It is not used in conjunction with antiplatelet drugs, serotonin reuptake inhibitors, anticoagulants, thrombolytics, as this will cause bleeding.

Meloxicam injections are not prescribed for patients taking lithium products. If the patient uses Methotrexate, then Movalis is not included in therapeutic regimens or treatment is carried out with constant monitoring of liver and kidney function.

Terms of sale

Movalis injection solution is dispensed from pharmacies after presenting a prescription from a doctor.

Cost of preparation

The average cost of packing Movalis No. 3 is 640 rubles, No. 5 is 860 rubles.

Terms and conditions of storage

Movalis should be stored at room temperature in places protected from direct sunlight. The shelf life of the injection solution is 5 years. It is unsuitable for treatment with a change in color, smell, precipitation. Small children should not have access to the storage location of the drug.

Analogs of injections Movalis

Structural analogues of the drug – Meloxicam, Mesipol, Amelotex, Arthrosan. Orthofen, Ksefokam, Voltaren, Ketorol, Ketorolak possess similar therapeutic properties.

Patient reviews and expert opinion

Doctors prefer Movalis because of the rapid manifestation of analgesic, anti-inflammatory, antiexudative action. The drug is characterized by high clinical efficacy, a low likelihood of developing local and systemic adverse reactions.

Patients evaluated the ability of the drug to eliminate the most severe pain arising from exacerbations of joint and spinal pathologies. Its undoubted advantage is the possibility of a single use.

Shishkevich Vladimir

Shishkevich Vladimir, orthopedic and traumatologist, project editor-in-chief ExpertNews. It specializes in the treatment of diseases in orthopedic, traumatological, vertebrological profiles

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